BPC-157

BPC-157 | Gastric Pentadecapeptide for Tissue Repair & Musculoskeletal Research

■ For Research Use Only. Not for human or veterinary use. Not a drug, supplement, or food additive.
Intended exclusively for in-vitro and laboratory research by qualified investigators.

BPC-157 – 10mg | 20mg | 40mg
Category: Peptide Research Compounds / Musculoskeletal Research / Gastrointestinal & Tissue Repair Biology

Disclaimer

ATTENTION: PRIMALRESEARCHLABS.COM PRODUCTS ARE INTENDED FOR LABORATORY RESEARCH AND IN-VITRO STUDIES ONLY.

All information presented on this site is for educational and research purposes related to scientific investigation.

These products are strictly not for human or veterinary use, consumption, or diagnostic applications.

They are not pharmaceuticals, food additives, or dietary supplements.

By purchasing from PrimalResearchLabs.com, you acknowledge that you are a qualified researcher operating in a controlled laboratory environment and agree to follow all applicable local, state, and federal laws regarding the handling and use of research chemicals.

Handle all materials with appropriate personal protective equipment (PPE) and laboratory safety protocols.

Biology

BPC-157 is a stable synthetic gastric pentadecapeptide, consisting of 15 amino acids derived from the endogenous Body Protection Compound originally isolated from human gastric juice.

It has been extensively studied in preclinical research for its ability to support tendon, ligament, muscle, and gastrointestinal repair, promote angiogenesis, modulate nitric oxide signaling, and enhance cytoprotection.

Its remarkable stability under gastric and physiological conditions makes it a versatile tool for in-vitro and in-vivo experimental designs in connective tissue biology, wound healing, and regenerative research.

This product is intended solely for in-vitro and preclinical research use and is not for human or veterinary consumption.

Key Research Applications

1. Tendon Healing & Connective Tissue Regeneration

• Fibroblast Outgrowth & Migration: Accelerates tendon fibroblast outgrowth and enhances in-vitro migration via the FAK-paxillin pathway.
• Cell Survival Under Oxidative Stress: Promotes fibroblast survival under H₂O₂-induced oxidative stress, mimicking ischemic injury conditions.
• Tendon-to-Bone Healing: Improves tendon reattachment in preclinical models with increased functional index, load-to-failure, and collagen organization.

Supporting Study:
Chang, C.H. et al. (2011) — Journal of Applied Physiology, 110(3), 774–780
PubMed – PMID: 21030672

2. Angiogenesis & Vascular Growth

• VEGF Upregulation: Modulates angiogenesis in muscle and tendon healing through VEGF expression.
• VEGFR2-Akt-eNOS Pathway Activation: Promotes endothelial activity and nitric oxide production to support vascular regeneration.
• Context-Dependent NO Modulation: Regulates nitric oxide system bidirectionally, offering broad cytoprotective effects.

Supporting Study:
Brcic, L. et al. (2010) — Journal of Physiology and Pharmacology, 61(2), 217–227
PubMed – PMID: 20388964

3. Musculoskeletal Soft Tissue Healing

• Broad Tissue Repair Profile: Improves outcomes in tendon, ligament, muscle, and bone injury models through growth factor pathway enhancement and inflammatory cytokine modulation.
• Growth Hormone Receptor Upregulation: Increases expression in tendon fibroblasts to augment connective tissue repair.
• Safety Profile: No mutagenic, genotoxic, hepatotoxic, or nephrotoxic effects observed in preclinical studies.

Supporting Study:
Gwyer, D. et al. (2019) — Cell and Tissue Research, 377, 153–159
PubMed – PMID: 30915550

Recommended Research Concentrations

Why Choose Primal Research for Your BPC-157 Studies?

• ≥98% HPLC-verified purity — critical for reproducible fibroblast migration and angiogenesis assays
• Independent third-party batch testing with COA available on request
• Lyophilized powder for optimal stability — maintains activity across a wide pH range
• Available in 10mg, 20mg, and 40mg quantities — supports multi-timepoint in-vitro and in-vivo protocols

Storage & Handling

• Store at -20°C, desiccated, and protected from light
• Soluble in sterile water or bacteriostatic water
• Prepare fresh solutions prior to each experiment
• Avoid repeated freeze-thaw cycles

Technical Specifications

Compound: BPC-157 (Body Protection Compound-157)
Sequence: Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Molecular Weight: 1419.5 g/mol
Molecular Formula: C62H98N16O22
CAS Number: 137525-51-0
Purity: ≥98% (HPLC Verified)
Form: Lyophilized powder — available in 10mg, 20mg, 40mg
Storage: -20°C, desiccated, light-protected
Solubility: Soluble in sterile water or bacteriostatic water
COA: Available per batch on request

Advance Your Research

Order your BPC-157 today to support advanced research in tissue repair, musculoskeletal regeneration, and gastrointestinal cytoprotection.

Final Disclaimer:
Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.