Ipamorelin

Ipamorelin

Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.

Please note, to maintain the quality and integrity of every product, all orders are fulfilled on a made-to-order basis. Please allow 7–14 days for processing and delivery. You will receive tracking details as soon as your order is dispatched.

Research Use Only.

This compound is supplied strictly for in vitro research purposes. It is not approved by the FDA and is not intended for human consumption, therapeutic, diagnostic, or veterinary use. By purchasing, you confirm you are a qualified researcher aged 18+.

Description

Selective Ghrelin Receptor Agonist | Growth Hormone Secretagogue Research Compound

For Research Use Only. Not for human or veterinary use. Not a drug, supplement, or food additive.

Intended exclusively for in-vitro and laboratory research by qualified investigators.

Ipamorelin – 10mg
A Selective Ghrelin Receptor Agonist for Growth Hormone Axis Research

Category: Peptide Research Compounds / Endocrinology Research / GH Axis Biology


Disclaimer

ATTENTION: PrimalResearchLabs.com products are intended for laboratory research and in-vitro studies only. All information presented is for educational and research purposes related to scientific investigation.

These products are strictly not for human or veterinary use, consumption, or diagnostic applications. They are not pharmaceuticals, food additives, or dietary supplements.

By purchasing from PrimalResearchLabs.com, you acknowledge that you are a qualified researcher operating in a controlled laboratory environment. Adhere to all applicable local, state, and federal laws and regulations regarding handling and use of research chemicals. Use appropriate personal protective equipment (PPE) and follow laboratory safety protocols.


Biology

Ipamorelin is a synthetic pentapeptide growth hormone secretagogue that selectively binds to the ghrelin receptor (GHS-R1a), stimulating pulsatile growth hormone (GH) release in preclinical and clinical research models.

It has been extensively studied for its high receptor selectivity and its ability to promote GH secretion without significantly increasing ACTH, cortisol, or prolactin levels compared with earlier GHRP compounds.

Ipamorelin is of particular interest in endocrine and metabolic research due to its ability to preserve physiological GH pulse patterns while supporting downstream insulin-like growth factor-1 (IGF-1) signaling pathways. Its selectivity and favorable pharmacodynamic profile make it a valuable tool for in-vitro and in-vivo experimental design across growth hormone biology, metabolic regulation, and recovery-related studies.

This product is intended solely for in-vitro and preclinical research use and is not for human or veterinary consumption.


Key Research Applications of Ipamorelin

1. Growth Hormone Secretion & Ghrelin Receptor Signaling

Ipamorelin demonstrates significant activity in GH axis studies through:

  • Selective GHS-R1a Activation: Stimulates GH release through ghrelin receptor binding with minimal activation of non-target endocrine pathways.
  • Pulsatile GH Secretion: Preserves physiologic GH release patterns in contrast to continuous stimulation models.
  • Reduced Off-Target Hormonal Effects: Exhibits minimal impact on ACTH, cortisol, and prolactin secretion.

Supporting Studies:
Raun, K. et al. — European Journal of Endocrinology
“Ipamorelin is a highly selective growth hormone secretagogue that stimulates GH release without significant effects on ACTH or cortisol secretion.” ■ PubMed – PMID: 9849825


2. GH/IGF-1 Axis & Anabolic Signaling

Investigated in downstream endocrine pathways through:

  • IGF-1 Modulation: Increases circulating IGF-1 levels secondary to GH stimulation in research models.
  • Protein Synthesis Signaling: Enhances anabolic signaling pathways associated with tissue repair and regeneration.
  • Skeletal Muscle Research: Applied in studies examining endocrine support for muscle growth and recovery.

Supporting Studies:
Jørgensen, J.O.L. et al. — Growth Hormone & IGF Research
“Growth hormone secretagogues stimulate GH release and downstream IGF-1 production while preserving physiologic secretion patterns.” ■ PubMed – PMID: 11553901


3. Metabolic Regulation & Lipid Metabolism

Explored in metabolic pathway studies through:

  • Lipolysis Support: Promotes fat metabolism via GH-mediated signaling pathways.
  • Energy Regulation: Influences metabolic efficiency and substrate utilization in experimental models.
  • Endocrine Metabolic Research: Used in studies evaluating GH-related metabolic outcomes.

Supporting Studies:
Smith, R.G. et al. — Endocrine Reviews
“Growth hormone secretagogues regulate metabolic processes including lipolysis and energy homeostasis through GH-dependent mechanisms.” ■ PubMed – PMID: 15769903


Recommended Research Concentrations

For laboratory research reference only. Not for human or veterinary use.

Research Model Suggested Concentration Administration
In-vitro receptor assays 1–100 nM Assay buffer
GH secretion studies 1–100 nM Cell culture media
Animal models (rodents, SC) 0.1–1 mg/kg Injection

Why Choose Primal Research for Your Ipamorelin Studies?

  • ≥98% HPLC-verified purity — critical for ghrelin receptor binding and GH secretion accuracy
  • Independent third-party batch testing with COA available on request
  • Lyophilized powder for maximum stability and long-term storage
  • Available in 10mg quantity — supports both focused and extended endocrine research protocols

Storage & Handling

  • Store at -20°C, desiccated and protected from light
  • Soluble in sterile water or bacteriostatic water
  • Prepare fresh solutions prior to each experiment
  • Avoid repeated freeze-thaw cycles

Technical Specifications

  • Compound: Ipamorelin
  • Molecular Weight: ~711.85 g/mol
  • Molecular Formula: C38H49N9O5
  • Purity: ≥98% (HPLC Verified)
  • Form: Lyophilized powder — 10mg
  • Storage: -20°C, desiccated, light-protected
  • Solubility: Soluble in sterile water or bacteriostatic water
  • COA: Available per batch on request

Advance Your Endocrine Research

Order your Ipamorelin 10mg today to support advanced research in growth hormone signaling, ghrelin receptor biology, and metabolic science.

Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.

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Shipping & Storage
Shipping: Ships within 48 hours. Temperature-appropriate packaging. Discreet labeling.
Lyophilized: Stable at −20°C for up to 24 months when kept dry and protected from light.
Reconstituted: Store at 2–8°C. Use within 28 days. Do not freeze after reconstitution.
Diluent: Bacteriostatic water (BW) recommended for multi-dose use. See Protocols.