TA-1

Thymosin Alpha-1 (TA-1) –  10mg
A 28-Amino-Acid Thymic Peptide for Advanced Immunology Research
An Immunomodulatory Thymic Peptide for T-Cell and Innate Immunity Studies

Category: Peptide Research Compounds / Immunology / Thymic Peptide Biology

For Research Use Only. Not for human or veterinary use. Not a drug, supplement, or food additive. Intended exclusively for in-vitro and laboratory research by qualified investigators.

DISCLAIMER
ATTENTION: PRIMALRESEARCHLABS.COM products are intended for laboratory research and in-vitro studies only. All information presented is for educational and research purposes related to scientific investigation. These products are strictly not for human or veterinary use, consumption, or diagnostic applications. They are not pharmaceuticals, food additives, or dietary supplements. By purchasing from PRIMALRESEARCHLABS.COM, you acknowledge that you are a qualified researcher operating in a controlled laboratory environment. Adhere to all applicable local, state, and federal laws and regulations regarding handling and use of research chemicals. Use appropriate personal protective equipment (PPE) and follow laboratory safety protocols.

BIOLOGY
Thymosin Alpha-1 (TA-1) is a 28-amino-acid peptide originally isolated from thymic tissue and recognized as a key endogenous modulator of immune function. It influences the maturation, differentiation, and activity of T lymphocytes and modulates both adaptive and innate immune signaling pathways.

TA-1 has been extensively investigated across preclinical and clinical research models examining immune regulation, including studies of viral infection, sepsis, inflammation, and host immune response. Its activity on dendritic cells, T-cell subsets, and cytokine expression makes it a valuable tool for in-vitro and in-vivo experimental design across immunology and infectious-disease research.

This product is intended solely for in-vitro and preclinical research use and is not for human or veterinary consumption.

KEY RESEARCH APPLICATIONS OF THYMOSIN ALPHA-1

1. T-Cell Maturation & Adaptive Immunity
TA-1 demonstrates significant activity in immunology studies through:
• T-Lymphocyte Modulation: Influences maturation and differentiation of T-cell subsets.
• CD4+/CD8+ Dynamics: Studied for effects on T-cell population ratios.
• Cytokine Regulation: Modulates expression of immune signaling molecules.
Supporting Studies:
Garaci, E. et al. — Frontiers in Medicine. “Phenotypic drug discovery: a case for thymosin alpha-1, an immune-modulating peptide.” PubMed – PMID: 38903817

2. Innate Immunity & Host Response
Investigated in immune-regulation and infection models through:
• Dendritic Cell Activity: Studied for effects on antigen-presenting cell function.
• Inflammatory Modulation: Examined in models of immune dysregulation.
• Host Defense Pathways: Applied in studies of immune competence.
Supporting Studies:
Li, J. et al. — International Immunopharmacology. “Thymosin alpha 1 based immunomodulatory therapy for sepsis: a systematic review and meta-analysis.” PubMed – PMID: 25532482

3. Immune Competence in Disease Models
Explored in broader immunology research through:
• Immunomodulatory Therapy: Studied as an adjunct in immune-compromised models.
• Lymphocyte Recovery: Examined for effects on immune cell populations.
• Translational Immunology: Applied across infectious-disease research models.
Supporting Studies:
Liu, F. et al. — BMC Infectious Diseases. “The efficacy of thymosin alpha 1 as immunomodulatory treatment for sepsis: a systematic review of randomized controlled trials.” PubMed – PMID: 27633969

RECOMMENDED RESEARCH CONCENTRATIONS
For laboratory research reference only. Not for human or veterinary use.
• In-vitro immune assays — 1-100 nM — Assay buffer
• T-cell / dendritic cell culture — 1-50 nM — Cell culture media
• Animal models (rodents, SC) — 0.05-0.2 mg/kg — Injection

WHY CHOOSE PRIMAL RESEARCH FOR YOUR THYMOSIN ALPHA-1 STUDIES?
• ≥98% HPLC-verified purity — critical for immune signaling studies
• Independent third-party batch testing with COA available on request
• Lyophilized powder for maximum stability and long-term storage
• Available in 5mg and 10mg quantities — supports scalable immunology protocols

STORAGE & HANDLING
• Store at -20°C, desiccated and protected from light
• Soluble in sterile water or bacteriostatic water
• Prepare fresh solutions prior to each experiment
• Avoid repeated freeze-thaw cycles

TECHNICAL SPECIFICATIONS
Compound: Thymosin Alpha-1 (TA-1)
Molecular Weight: ~3108 g/mol
Purity: ≥98% (HPLC Verified)
Form: Lyophilized powder — 5mg and 10mg
Storage: -20°C, desiccated, light-protected
Solubility: Soluble in sterile or bacteriostatic water
COA: Available per batch on request

ADVANCE YOUR RESEARCH
Order your Thymosin Alpha-1 today to support advanced research in thymic peptide biology, T-cell immunology, and host immune response modeling.

Primal Research products are sold strictly for in-vitro and laboratory research use only. Not for human or veterinary consumption. Not intended to diagnose, treat, cure, or prevent any disease or condition. Purchasers are responsible for compliance with all applicable local, state, and federal regulations.